Increase Of Concentration Of Ethyl Acetate

Increase Of Concentration Of Ethyl Acetate Firstly the aim of the experiment is to determine the yield, conversion and reaction rate by employing the principles of material balance with chemical reaction for batch reactions. The purpose of the experiment is to find out the factors affecting the rate of reaction to increases the conversion rate the yield of product produced. The hypothesis of the experiment is that the increase of concentration of Ethyl Acetate would also increase the rate of reaction. From two different concentrations of Ethyl Acetate (0.01M and 0.02M) have shown that the 0.02M of Ethyl Acetate shows a increase in the rate of reaction and conversion rate of Sodium Hydroxide to Sodium Acetate. Secondly the theory part shows the definitions of terms like saponification, batchwise reactions and factors that affect the rate of reaction. The most important definition is the saponification which is the hydrolysis of an ester under basic conditions to form an alcohol and the salt of a carboxylic acid. Thirdly, the procedure section shows how to carry out the 3 major steps which are preparation of the reactant, the experimental setup and the procedures to carry out the experiment. This is followed by the results and calculations which is about the calculation of the conversion percentage and yield of the reactions of different concentrations of Ethyl Acetate carried out in the experiment. After the results and calculations, is the discussion part which discusses the results obtained, states some precautions to be taken while carrying out the experiment and the factors that affect the results. Lastly the conclusion concludes the report by stating if the aim of the experiment had been reached and it also states that the hypothesis that the higher the concentration of the reactant, the faster the rate of reaction and conversion, has been proven. REPORT ON MATERIAL BALANCE WITH CHEMICAL REACTION 1. Introduction 1.1 Background Literature Conversion of sodium hydroxide into sodium acetate is called saponification. It is the process of making soap. It is the reaction between an ester with a metallic base and water. It is also related to the process used to convert natural fats into soap. (Donohue 2009) An alkali is a soluble salt of an alkali metal like sodium. It is used in soap-making whereby it was obtained from the ashes of plants. Now, the term alkali describes a base which neutralizes an acid. (Donohue 2009) Alkalis used in soap making are sodium hydroxide (NaOH), also called caustic soda; and potassium hydroxide (KOH), also called caustic potash. (Donohue 2009) Example: An example of the reaction is: (Therese Lotts Saponification Calculator Standalone spreadsheet for calculating saponification values in handmade soapmaking. ) (http://www.freepatentsonline.com/6751527.html) 1.2 Aim The aim of this experiment is to determine the yield, conversion and reaction rate by employing the principles of material balance with chemical reaction for batch reactions. This will also enable us to find out factors to improve the yield and the rate of conversion and reaction. 1.3 Hypothesis The hypothesis of the experiment is that if the concentration is high, the yield together with the rate of conversion and reaction would also increase. Thus, from a 0.02M concentration of Ethyl Acetate and 0.01M concentration of Ethyl Acetate, the 0.02M concentration would have a higher yield, rate of conversion and reaction. This is because at the start of the experiment the conductivity value was high but as the reaction precedes the conductivity value decreases showing the concentration and number of moles. 2. Theory 2.1 Saponification Saponification is the hydrolysis of an ester under basic conditions to form an alcohol and the salt of a carboxylic acid. Saponification is commonly used to refer to the reaction of a metallic alkali with a fat or oil to form soap. Saponifiable substances are those that can be converted into soap. In the experiment the desired product is sodium acetate. (Donohue 2009) 2.2 Batchwise Reaction A batchwise reaction is a reaction where by reactants are put in and the reaction is started. After the reaction has ended, the products are taken out and the equipment and all are washed to be prepared for the next experiment. Unlike steady state reaction it does not have a continuous input and output. (Singapore Polytechnic 2009) 2.3 Percentage Conversion Xa = moles of A reacted Moles of A fed into the reactor x100% It is defined as a fraction of reactants or feed that successfully reacted to form the desired product. The above formula calculates the amount of reacts converted into products. (Singapore Polytechnic 2009) 2.4 Yield of A Product YP = Moles of desired product formed Moles of reactant fed into the reactor Yield has 3 definitions. Firstly it is amount of desired product formed based on the amount of limiting reactants feed into the reaction. Secondly it is the amount of desired product obtained divided by the amount of reactant consumed. Lastly, it is also defined as the amount of product obtained divided by the theoretically amount of limiting reactant consumed. The above reaction calculates the amount yield based on just the limiting reactant. (Singapore Polytechnic 2009) 2.5 Rate of Reaction The rate of reaction is the amount of time taken for the chemicals to react totally. (Singapore Polytechnic 2009) 2.6 Surface Area To Volume Ratio The surface area to the volume ration affects the rate of reaction. The smaller the particle, the larger its exposed surface area. With a larger exposed surface area more particles can collide with one another causing more reactions to take place within a shorter amount of time. (Purchon 2006) 2.7 Presence of a Catalyst If a catalyst is involved in a reaction, the amount of energy needed to start the reaction (activation energy) decreases. Thus, the molecules in the reactions will gain more energy that is equal to or more than the activation energy. The higher amount of energy a molecules has, the more active it will become and more collisions will occur increasing the rate of reaction. However a catalyst is not involved in this experiment. (Purchon 2006) 2.8 Pressure Pressure is another factor that affects the rate of reaction. Pressure mainly affects gases. Gases can be compressed. Thus, as pressure increases, gaseous molecules are closely packed together which allows them to collide more frequently with one another. This is almost the same as changing the concentration as the number of molecules is increased within a specific area. However the reaction is a liquid-liquid reaction so pressure does not affect the reaction in this experiment. (Purchon 2006) 2.9 Concentration Concentration affects the rate of reaction. The higher the concentration, the number of particles within a specific area increases. Thus, molecules are closely packed together and this increases the number of collisions between molecules so the rate of reaction increases. Concentration is similar to pressure where by the number of molecules in a specific area increases. (Purchon 2006) 2.10 Temperature Temperature also affects the rate of reaction. If the temperature is higher, the energy levels of the molecules increases and they would tend to more faster. Thus, this results in more effective collisions in a shorter amount of time. (Purchon 2006) 2.11 Conductivity Unlike Sodium Hydroxide, Ethyl acetate, Ethanol and Sodium acetate have negligible conductivity. Thus the conductivity value of the reaction is measured by the conductivity of Sodium Hydroxide. The conductivity is used to find the concentration of Sodium Hydroxide as the reaction proceeds. (Singapore Polytechnic 2009) Fig.1) Graph of conductivity values of Sodium Hydroxide against the concentration of Sodium Hydroxide.) 3. Procedure 3.1 Preparation of chemicals The MSDS of sodium hydroxide and ethyl acetate was read and the handling and disposal of the chemicals must be familiarized before the start of the experiment. Disposable gloves and chemical goggles were put on when preparing and handling the chemicals.500 ml of 0.01 M sodium hydroxide solution and 500 ml of ethyl acetate solution to the required concentration as discussed in Questions 1 and 2 of Pre-experiment Assessment was prepared. (CP4047 Lab Manual) 3.1.1 Preparing 500 ml of 0.01 M sodium hydroxide solution: The required volume of 0.1 M NaOH stock solution was measured using a measuring cylinder and pour into the 500 ml volumetric flask. The solution in the volumetric flask was topped up with de-ionized water to the 500 ml-mark. A Stopper was placed on the flask, and it was shaken and inverted to mix the solution. (CP4047 Lab Manual) 3.1.2 To prepare 500 ml of ethyl acetate solution: About 250 ml de-ionized water was poured into a 500 ml volumetric flask first. The required volume was measured using the micropipettor. The stock solution was dispensed into the 500 ml volumetric flask.The solution in the volumetric flask was topped up to the 500 ml-mark. A stopper was placed on the flask, and was shaken and inverted to mix the solution. (CP4047 Lab Manual) 3.2 Experimental setup (CP4047 Lab Manual) 3.3 Carrying out the Experiment The prepared sodium hydroxide solution was poured into the reactor. The reaction conditions were adjusted to the predetermined levels (based on experimental methodology discussed with Lecturer). The reaction conditions were recorded, Eg. temperature, stirring speed, concentrations and volumes of reactants. Conductivity meter probe was positioned into the reacting mixture. The ethyl acetate solution was poured in and the timer was started immediately. The conductivity values (mS/cm) at a regular interval of 1 minute for 30 minutes of reaction time was recorded. After 30 minutes of reaction, the stirring device was stopped and the magnetic stir bar was removed from the mixture using the magnetic rod. The conductivity probe was also removed and rinsed thoroughly with de-ionised water. The reaction product mixture was poured into the plastic waste container. The glassware was rinsed and the experiment was repeated based on experimental methodology discussed with the Lecturer. At the end of the experiment, the conductivity probe was removed from the reacting mixture and rinsed thoroughly with de-ionised water. All chemicals were disposed in the plastic waste container and were brought to the waste together with any unused reactants to W314 for proper treatment and disposal. All the used glass-wares was rinsed and tidied up the work space. (CP4047 Lab Manual) 4. Results and Calculations 4.1 Determining the Yield of Sodium Acetate at 15 Minutes The yield of Sodium Acetate at 15minutes is determined with the concentration of Sodium Hydroxide as with the concentration, the number of mole of sodium hydroxide can be found out. Also, with the molar ratio of Sodium Hydroxide and Ethyl Acetate, the number of moles of Ethyl Acetate can be determined. With the use of the yield formula, the yield of Ethyl Acetate can be calculated. 4.2 Yield When 0.01M of Ethyl Acetate Used 5. Discussion 5.1 Factors Affecting Rate of Reaction Firstly the concentrations of Ethyl Acetate used were 0.01M and 0.02M which means that for 0.01M of Ethyl Acetate was obtained by diluting 0.49cm3 of pure Ethyl Acetate and 0.02M was obtained by diluting 0.92cm3 of pure Ethyl Acetate. By comparing the graphs (Fig 3 and 4) above, the reaction (0.02M) was the fastest. This was due to the concentration factor. The higher the concentration, the faster the rate of reaction as the increase in concentration means that there are more molecules in a specific area. Other factor like temperature and pressure were keep at a constant (standard room conditions). There was no catalyst involved the experiment. Thus, these other factors did not affect the rate of reaction. 5.2 Factors Affecting Conversion and Yield The conversion of Sodium Hydroxide and the yield of Sodium Acetate will never be a 100% due to the technical equipment and unforced human errors. It is also due to constrains in the lab like equipment or the duration of the experiment. The longer the reaction, more conversion and yield could have been produced. 5.3 Factors Affecting the Conductivity Values The concentration of Sodium Hydroxide affects the conductivity value of the reaction. If the concentration of Sodium Hydroxide is high, the conductivity value will also be high. Thus, as the reaction proceeds, the conductivity drops as the concentration of the Sodium Hydroxide decreases as it is being reacted away. For the 0.01M reaction, Fig 4.2.2 show that the concentration decreases significantly. However, for the 0.02M reaction, Fig 4.3.2 shows some fluctuations in the drop of the concentration of Sodium Hydroxide. This could be because of the equipment. The equipment, the conductivity probe and the machine has been known to turn off randomly during the reaction. Thus there was some irregularities in the drop of concentration for the 0.02M reaction. 5.4 Precautions to Be Taken During the experiment the Ethyl Acetate should always be handled in the fume hood as it would decompose in the open, thus affecting the concentration of the Ethyl Acetate and to prevent it from spilling anywhere else in the laboratory. Gloves should also be worn to prevent bacteria from contaminating the reaction or chemicals and to also protect our hands from the chemicals. Goggles should also be worn to protect our eyes from chemicals splashing into our eyes. 5.5 Comparison of conversion and yields of different concentration of Ethyl Acetate The yield of the reaction of 0.01M Ethyl Acetate is 0.62 while the yield of the reaction of 0.02M Ethyl Acetate is 0.76. The second reaction of 0.02M has a higher yield due to the higher concentration of Ethyl Acetate. This is because the concentration of the reactants is more due to the increase in concentration of Sodium Hydroxide thus, producing more products whereby the yield of Sodium Acetate increases. However both the experiments did not produce a 100% yield because of human error and constrains of technical equipment. Even if a catalyst was added, the yield will be the same as the catalyst will only increase the rate of reaction and affect the yield. 6. Conclusion In conclusion, the higher the concentration of Ethyl Acetate used, the faster the rate of reaction together with a higher conversion percentage of Sodium Hydroxide. The concentration of Sodium Hydroxide affects the conductivity values of the reaction because the results show that the conductivity decreases as the reaction proceeds because the concentration of Sodium Hydroxide also decreases as the Sodium Hydroxide was being reacted away. Therefore, the hypothesis is proven to be true. The aim of the experiment was met as results state that with a higher concentration of Ethyl Acetate, the rate of reaction together with the rate of conversion increases. The concentration of the Ethyl Acetate reacting with Sodium Hydroxide in a reactor as time passes by was studied. However the experiment could be improved by adding in a catalyst or increasing the temperature to increase the rate of reaction and conversion rate.

Advantages and Disadvantages of Genetic Engineering Essay

Genetic Engineering: Advantages and Disadvantages essay. During the latter stage stages of the 20th century, man harnessed the power of the atom, and not long after, soon realised the power of genes. Genetic engineering is going to become a very mainstream part of our lives sooner or later, because there are so many possibilities advantages (and disadvantages) involved. Here are just some of the advantages :Disease could be prevented by detecting people/plants/animals that are genetically prone to certain hereditary diseases, and preparing for the inevitable. Also, infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen.Animals and plants can be ‘tailor made' to show desirable characteristics. Genes could also be manipulated in trees for example, to absorb more CO2 and reduce the threat of global warming.Genetic Engineering could increase genetic diversity, and produce more variant alleles which could also be crossed over and implanted into other species. It is possible to alter the genetics of wheat plants to grow insulin for example. Of course there are two sides to the coin, here are some possible eventualities and disadvantages.Nature is an extremely complex inter-related chain consisting of many species linked in the food chain. Some scientists believe that introducing genetically m odified genes may have an irreversible effect with consequences yet unknown.Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature. Genetic engineering may be one of the greatest breakthroughs in recent istory alongside the discovery of the atom and space flight, however, with the above eventualities and facts above in hand, governments have produced legislation to control what sort of experiments are done involving genetic engineering. In the UK there are strict laws prohibiting any experiments involving the cloning of humans. However, over the years here are some of the experimental ‘breakthroughs' made possible by genetic engineering.At the Roslin Institute in Scotland, scientists successfully cloned an exact copy of a sheep, named ‘Dolly'. This was the first successful cloning of an animal, and most likely the first occurrence of two organisms being g enetically identical. Note : Recently the sheep's health has deteriorated detrimentallyScientists successfully manipulated the genetic sequence of a rat to grow a human ear on its back. (Unusual, but for the purpose of reproducing human organs for medical purposes)Most controversially, and maybe due Essay topic: advantages and disadvantages of genetic engineering. Discuss The development of genetic engineering has increased notably in the last few years.Some people support the investment in this field whereas others are against to. In this essay I shall delve into both sides before forming an opinion. Genetic engineering is the process of manipulating the genes of an organism. People supporting it use argue that for instance farmers could have crops more resistant to insects and diseases, and many genetically modified crops can grow faster. These advantages can be extremely positive for food production in developing nations where people starve. Faster growing cereals, fruits and veg etables would mean more profit.Moreover, some medicines and vaccines are obtained throw genetic engineering process. An important breakthrough that genetic engineering can bring to society is that some inherited diseases would no longer exist. Some genes can be modified before a baby is born improving its life expectancy. It could be said then that genetic engineering might cure some diseases. However there are ethical concerns about it use. Some ecologists warn about the disaster consequences to the Earth. They say that genetically modified crops can affect seriously whole ecosystems as the food chain can be broken if crops are more resistant to predators.Furthermore, some people are strongly against to human genetic engineering as parents might want to choose their children's characteristics. They support this argument saying that it would be unnatural and in some religions would be unacceptable. Society an human evolution would change completely. To sum up, both sides have strong arguments to support their opinions. As far as my opinion is concerned genetic engineering can bring to humans longer and healthier lives. However there is a thin line between what is ethical and what not What are the disadvantages of genetic engineering?* 5 years ago Best Answer  Ã¢â‚¬â€œ Chosen by Voters 1. probably it would be costly 2. a single mistake has devastating repercussions 3. it borders on the issue of ethics and morality 4. an increasing demand for genetic modification which effetively increases discontentment for the self or for the original genetic configuration of an organism 5. prospect of creating new species might create natural imbalances especially on the habitats and feeding habits of other animals (by creating a new species, competition might arise, or it might be a predator to a prey who are already endangered, or for its own survival, it might need to destroy the habitats of others) 6. nexpected but undetected mutations can generally alter the future in unpleasant ways. What are the advantages and disadvantages of genetic engineering?Answer: advantages:1. Disease could be prevented by detecting people/plants/animals that are genetically prone to certain hereditary diseases, and preparing for the inevitable. Also, infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen.2. Another of genetic engineering is that diseases could be prevented by detecting people that are genetically prone to certain hereditary diseases, and preparing for he inevitable. As well as preventing disease, with genetic engineering infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen3. Animals and plants can be ‘tailor made' to show desirable characteristics. Genes could also be manipulated in trees for example, to absorb more CO2 and reduce the threat of global warming.4. Genetic Engineering could increase genetic diversity, and produce mor e variant alleles which could also be crossed over and implanted into other species. It is possible to alter the genetics of wheat plants to grow insulin for example.5. Another advantage of genetic engineering is that animals and plants can be made to have desirable characteristics which could help solve some of the world's problems. For example in trees, genes could be manipulated to absorb more carbon dioxide. This would help reduce global warming, and thus solve one of the biggest problems earth faces.Disadvantages:1. Nature is an extremely complex inter-related chain consisting of many species linked in the food chain. Some scientists believe that introducing genetically modified genes may have an irreversible effect with consequences yet unknown.2.Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature.3. Another reason why people think that using genetically mod ified crops and plants is a disadvantage is that they think it will increase our reliance on pesticides, which have a harmful effect on the environment.4. Another disadvantage of Genetic Engineering is Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature. Also it brings into question Darwin's theory of â€Å"the survival of the fittest†, if this theory has worked over the last 20 centuries , why change it? †¦ experimental ‘breakthroughs' made possible by genetic engineering.1. At the Roslin Institute in Scotland, scientists successfully cloned an exact copy of a sheep, named ‘Dolly'. This was the first successful cloning of an animal, and most likely the first occurrence of two organisms being genetically identical. Note : Recently the sheep's health has deteriorated detrimentally2. Scientists successfully manipulated the genetic sequence of a rat to grow a human ear on its back. Unusual, but for the purpose of reproducing human organs for medical purposes)   Most controversially, and maybe due to more liberal laws, an American scientist is currently conducting tests to clone himself. Genetic Engineering Advantages ; Disadvantages During the latter stage stages of the 20th century, man harnessed the power of the atom, and not long after, soon realised the power of genes. Genetic engineering is going to become a very mainstream part of our lives sooner or later, because there are so many possibilities advantages (and disadvantages) involved.Here are just some of the advantages :* Disease could be prevented by detecting people/plants/animals that are genetically prone to certain  hereditary  diseases, and preparing for the inevitable. Also, infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen.* Animals and plants can be ‘tailor made' to show desirabl e characteristics. Genes could also be manipulated in trees for example, to absorb more CO2  and reduce the threat of global warming. Genetic Engineering could increase genetic diversity, and produce more variant alleles which could also be crossed over and implanted into other species. It is possible to alter the genetics of wheat plants to grow insulin for example. Of course there are two sides to the coin, here are some possible eventualities and disadvantages.* Nature is an extremely complex inter-related chain consisting of many species linked in the food chain. Some scientists believe that introducing genetically modified genes may have an irreversible effect with consequences yet  unknown. Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature. Genetic engineering may be one of the greatest breakthroughs in recent history alongside the discovery of the ato m and space flight, however, with the above eventualities and facts above in hand, governments have produced legislation to control what sort of experiments are done involving genetic engineering. In the UK there are strict laws prohibiting any experiments involving the cloning of humans. However, over the years here are some of the experimental ‘breakthroughs' made possible by genetic engineering.* At the Roslin Institute in Scotland, scientists successfully cloned an exact copy of a sheep, named ‘Dolly'. This was the first successful cloning of an animal, and most likely the first occurrence of two organisms being genetically identical.Note : Recently the sheep's health has deteriorated detrimentally* Scientists successfully manipulated the genetic sequence of a rat to grow a human ear on its back. Unusual, but for the purpose of reproducing human organs for medical purposes)* Most controversially, and maybe due to more liberal laws, an American scientist is currently conducting tests to clone himself. Genetic engineering has been impossible until recent times due to the complex and microscopic nature of DNA and its component nucleotides. Through progressive studies, more and more in this area is being made possible, with the above examples only showing some of the potential that genetic engineering shows. For us to understand chromosomes and DNA more clearly, they can be mapped for future reference.More simplistic organisms such as fruit fly (Drosophila) have been chromosome mapped due to their simplistic nature meaning they will require less genes to operate. At present, a task named the Human Genome Project is mapping the human genome, and should be completed in the next ten years. The process of genetic engineering involves splicing an area of a chromosome, a gene, that controls a certain characteristic of the body. The enzyme endonuclease is used to split a DNA sequence and split the gene from the rest of the chromosome. For example, this ge ne may be programmed to produce an antiviral protein.This gene is removed and can be placed into another organism. For example, it can be placed into a bacteria, where it is sealed into the DNA chain using ligase. When the chromosome is once again sealed, the bacteria is now effectively re-programmed to replicate this new antiviral protein. The bacteria can continue to live a healthy life, though genetic engineering and human intervention has actively manipulated what the bacteria actually is. No doubt there are advantages and disadvantages, and this whole subject area will become more prominent over time.The next page returns the more natural circumstances of genetic diversity. Genetic Engineering in Humans Science is a fascinating subject with unthinkable power. Man, the greatest creation of God and a scientific marvel, has developed the ability to genetically modify and create ‘near perfect' life. The term genetic engineering was first used in Dragon's Island, a science fic tion novel by Jack Williamson in 1951. With the discovery of ‘Deoxyribonucleic Acid' or mitochondrial DNA by James Watson and Francis Crick, this fictional plot started to turn into a reality.Watson and Crick, with their experiments, could prove that DNA was the genetic material that was transferred generation to generation, with genetic information. This genetic information determined all the characteristics of a living being. The tiny, microscopic DNA contained all the genetic information related to the person, like the color of the eyes, the hair, skin tone, height, weight, IQ, EQ, diseases, disorders, etc. and even be able to determine a smile or the shape of nose. This blueprint of life is the most important ingredient of genetic engineering.Genetic engineering is carried out using five steps, that are: Gene of interest is isolated Transfer vector is inserted into the genes The vector is transferred into the organism that is to be modified The cells of an organism are tra nsformed The last step involves selection of successfully genetically modified organisms (GMO) from those who have failed to be modified. This biotechnology was first applied to produce synthetic human insulin. This technology was gradually used to apply to a number of vaccines and drugs, that would prove to be beneficial to the human race.It was applied to plants to produce genetically modified foods, with higher resistance to infections and high nutritional values. With the advancement in technologies and major breakthroughs in genetic engineering, more and more scientists working for private and government companies are spending time experimenting with the human genes. The completion of the Human Genome Project, in 2006, has given a major opening to medical companies, to carry out experiments and genetic tests using genetic engineering.ADVANTAGES of Human Genetic EngineeringIt could help prevent life-threatening and incurable diseases like cancer, Alzheimer's disease, even HIV/AI DS. There are cases like cardiomyopathy or susceptibility to viruses, that can be overcome with the help of this technology. Better drugs could be produced that are disease or gene specific and attack the specific genetic mutation in an individual, to help over come a disease or disorder. Many people want to live a longer, healthier life or are just afraid of death. Such people with a love of life, can place their bets on it to help them live longer.It is possible to increase the average life span of an individual to 100-150 years. And not just a longer life, but a healthy, long life, free from diseases and disorders. Although this may take a bit longer to achieve, but is does not seem impossible any longer. Women have a craze to look young and maintain their beauty for all eternity. The benefits may make it possible to slow down or reverse certain cellular metabolism, that may be able fulfill this desire to remain ‘forever young' for many dreamers in the near future. You may have heard of designer clothes, designer bags, designer shoes and even a designer nose.But have you heard of designer babies? Yes, designer babies are possible to be produced with its help in humans. Parents can choose the characteristics of their babies, like blond with blue eyes, high IQ, fair skin, etc. It may even be possible to choose the talent in your favorite idol to be manufactured (pun intended! ) in your baby, for example, a singer like Elvis Presley or maybe a great dancer like Michael Jackson. No, I am not joking, this is all possible with a bit of genetic engineering, within the blueprint of life – DNA.One could even try to create super-humans by incorporating specific features of certain animals. For example, one could have super-sharp vision like the hawk or could outrun a cheetah. One could create a ‘Superman' like human who is indestructible. Do you remember ‘Dolly Sheep'? This was a genetically modified, cloned sheep that is now dead for over 6 years. This world-famous sheep was cloned using the cell from the mammary gland of another sheep. Cloning, its another aspect can also be possible. There are many ethical issues of cloning and it is considered illegal by many governments around the world.It is a crime to clone humans now, but may be in our quest to produce the perfect beings, cloning will soon become a part of life. These are a few advantages of genetic engineering in humans. But as every coin has two sides, there are many disadvantages that cannot be overlooked. Disadvantages of Human Genetic Engineering Under the pretext of producing a cure for diseases and hereditary disorders, many researchers carry out experiments on genetically modifying humans. It can prove to be a bane if: In the pursuit of producing babies without any genetic defects or hereditary disorders, we may end up producing super humans.Just as the example I mentioned in the beginning of my article, we may have a line of humans that may spell doom t o those who are not genetically modified. Smarter humans means, larger brains, that may lead to babies with larger heads that have trouble passing through the birth canal of their mothers. This may cause trouble during birth and a rise in cesarean. Long life could lead to population problems. There may be stress on the natural resources and less living space. Although, you may live free of diseases, you may have a fight for survival for securing the basic necessities.Just like in the movie Gattaca, there may be a division between genetically engineered humans and those that are normal (just imagine, begin normal may prove to be curse in the future! ). People will no longer be discriminated on the basis of race, religion or creed, but actually on their genes! Human cloning may create problems of copies of men moving about freely around the world. If your clone turns out to be the one with a criminal streak, you may end up in jail for a crime committed by your clone. It is possible, i f you can't prove your innocence. Imagine someone else taking over your life, family, work, etc!The problem faced by many developing countries today, is female infanticide. It may help stop this cruel and barbaric custom of killing the innocent girl child. You may think this is an advantage, I say otherwise. It may help such narrow-minded, biased parents to actually choose the gender of the child. Therefore, more parents opting for a male child over a girl child. Thus, directly bringing an end to girl child killing as there will be no birth of the girl child! The idea of ‘Superman' may seem tantalizing, but its consequences may be very dangerous.Imagine a person who is virtually indestructible, may carry out crimes and becomes a danger to mankind. I can go on and on regarding the benefits of genetic engineering in humans, like end of hunger, no disease, cure for all ailments, long life, ageless beauty, super intelligent humans, etc. But, one should always give a second thought to all the disadvantages listed. It is often said, man should not attempt to ‘play God'. That's correct, but if God has bestowed us the power to make some beneficial changes to his creations, then we should surely do so wisely.Genetic engineers have turned into modern-day alchemists, who are searching for the ultimate elixir of life, to produce the genetically modified, perfect human. This precious knowledge is being exploited by greedy men, who are using it just to earn more money. Nothing is bad if exploited within limits. When we harness our present, we should keep in mind all the possible effects it will have on our future. We may not be alive to view the beauty and the ugliness of the future, but our beloved children may be facing the consequences. Advantages and Disadvantages of Genetic Engineering Essay Genetic Engineering: Advantages and Disadvantages essay. During the latter stage stages of the 20th century, man harnessed the power of the atom, and not long after, soon realised the power of genes. Genetic engineering is going to become a very mainstream part of our lives sooner or later, because there are so many possibilities advantages (and disadvantages) involved. Here are just some of the advantages :Disease could be prevented by detecting people/plants/animals that are genetically prone to certain hereditary diseases, and preparing for the inevitable. Also, infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen.Animals and plants can be ‘tailor made' to show desirable characteristics. Genes could also be manipulated in trees for example, to absorb more CO2 and reduce the threat of global warming.Genetic Engineering could increase genetic diversity, and produce more variant alleles which could also be crossed over and implanted into other species. It is possible to alter the genetics of wheat plants to grow insulin for example. Of course there are two sides to the coin, here are some possible eventualities and disadvantages.Nature is an extremely complex inter-related chain consisting of many species linked in the food chain. Some scientists believe that introducing genetically m odified genes may have an irreversible effect with consequences yet unknown.Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature. Genetic engineering may be one of the greatest breakthroughs in recent istory alongside the discovery of the atom and space flight, however, with the above eventualities and facts above in hand, governments have produced legislation to control what sort of experiments are done involving genetic engineering. In the UK there are strict laws prohibiting any experiments involving the cloning of humans. However, over the years here are some of the experimental ‘breakthroughs' made possible by genetic engineering.At the Roslin Institute in Scotland, scientists successfully cloned an exact copy of a sheep, named ‘Dolly'. This was the first successful cloning of an animal, and most likely the first occurrence of two organisms being g enetically identical. Note : Recently the sheep's health has deteriorated detrimentallyScientists successfully manipulated the genetic sequence of a rat to grow a human ear on its back. (Unusual, but for the purpose of reproducing human organs for medical purposes)Most controversially, and maybe due Essay topic: advantages and disadvantages of genetic engineering. Discuss The development of genetic engineering has increased notably in the last few years.Some people support the investment in this field whereas others are against to. In this essay I shall delve into both sides before forming an opinion. Genetic engineering is the process of manipulating the genes of an organism. People supporting it use argue that for instance farmers could have crops more resistant to insects and diseases, and many genetically modified crops can grow faster. These advantages can be extremely positive for food production in developing nations where people starve. Faster growing cereals, fruits and veg etables would mean more profit.Moreover, some medicines and vaccines are obtained throw genetic engineering process. An important breakthrough that genetic engineering can bring to society is that some inherited diseases would no longer exist. Some genes can be modified before a baby is born improving its life expectancy. It could be said then that genetic engineering might cure some diseases. However there are ethical concerns about it use. Some ecologists warn about the disaster consequences to the Earth. They say that genetically modified crops can affect seriously whole ecosystems as the food chain can be broken if crops are more resistant to predators.Furthermore, some people are strongly against to human genetic engineering as parents might want to choose their children's characteristics. They support this argument saying that it would be unnatural and in some religions would be unacceptable. Society an human evolution would change completely. To sum up, both sides have strong arguments to support their opinions. As far as my opinion is concerned genetic engineering can bring to humans longer and healthier lives. However there is a thin line between what is ethical and what not What are the disadvantages of genetic engineering?* 5 years ago Best Answer  Ã¢â‚¬â€œ Chosen by Voters 1. probably it would be costly 2. a single mistake has devastating repercussions 3. it borders on the issue of ethics and morality 4. an increasing demand for genetic modification which effetively increases discontentment for the self or for the original genetic configuration of an organism 5. prospect of creating new species might create natural imbalances especially on the habitats and feeding habits of other animals (by creating a new species, competition might arise, or it might be a predator to a prey who are already endangered, or for its own survival, it might need to destroy the habitats of others) 6. nexpected but undetected mutations can generally alter the future in unpleasant ways. What are the advantages and disadvantages of genetic engineering?Answer: advantages:1. Disease could be prevented by detecting people/plants/animals that are genetically prone to certain hereditary diseases, and preparing for the inevitable. Also, infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen.2. Another of genetic engineering is that diseases could be prevented by detecting people that are genetically prone to certain hereditary diseases, and preparing for he inevitable. As well as preventing disease, with genetic engineering infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen3. Animals and plants can be ‘tailor made' to show desirable characteristics. Genes could also be manipulated in trees for example, to absorb more CO2 and reduce the threat of global warming.4. Genetic Engineering could increase genetic diversity, and produce mor e variant alleles which could also be crossed over and implanted into other species. It is possible to alter the genetics of wheat plants to grow insulin for example.5. Another advantage of genetic engineering is that animals and plants can be made to have desirable characteristics which could help solve some of the world's problems. For example in trees, genes could be manipulated to absorb more carbon dioxide. This would help reduce global warming, and thus solve one of the biggest problems earth faces.Disadvantages:1. Nature is an extremely complex inter-related chain consisting of many species linked in the food chain. Some scientists believe that introducing genetically modified genes may have an irreversible effect with consequences yet unknown.2.Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature.3. Another reason why people think that using genetically mod ified crops and plants is a disadvantage is that they think it will increase our reliance on pesticides, which have a harmful effect on the environment.4. Another disadvantage of Genetic Engineering is Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature. Also it brings into question Darwin's theory of â€Å"the survival of the fittest†, if this theory has worked over the last 20 centuries , why change it? †¦ experimental ‘breakthroughs' made possible by genetic engineering.1. At the Roslin Institute in Scotland, scientists successfully cloned an exact copy of a sheep, named ‘Dolly'. This was the first successful cloning of an animal, and most likely the first occurrence of two organisms being genetically identical. Note : Recently the sheep's health has deteriorated detrimentally2. Scientists successfully manipulated the genetic sequence of a rat to grow a human ear on its back. Unusual, but for the purpose of reproducing human organs for medical purposes)   Most controversially, and maybe due to more liberal laws, an American scientist is currently conducting tests to clone himself. Genetic Engineering Advantages ; Disadvantages During the latter stage stages of the 20th century, man harnessed the power of the atom, and not long after, soon realised the power of genes. Genetic engineering is going to become a very mainstream part of our lives sooner or later, because there are so many possibilities advantages (and disadvantages) involved.Here are just some of the advantages :* Disease could be prevented by detecting people/plants/animals that are genetically prone to certain  hereditary  diseases, and preparing for the inevitable. Also, infectious diseases can be treated by implanting genes that code for antiviral proteins specific to each antigen.* Animals and plants can be ‘tailor made' to show desirabl e characteristics. Genes could also be manipulated in trees for example, to absorb more CO2  and reduce the threat of global warming. Genetic Engineering could increase genetic diversity, and produce more variant alleles which could also be crossed over and implanted into other species. It is possible to alter the genetics of wheat plants to grow insulin for example. Of course there are two sides to the coin, here are some possible eventualities and disadvantages.* Nature is an extremely complex inter-related chain consisting of many species linked in the food chain. Some scientists believe that introducing genetically modified genes may have an irreversible effect with consequences yet  unknown. Genetic engineering borderlines on many moral issues, particularly involving religion, which questions whether man has the right to manipulate the laws and course of nature. Genetic engineering may be one of the greatest breakthroughs in recent history alongside the discovery of the ato m and space flight, however, with the above eventualities and facts above in hand, governments have produced legislation to control what sort of experiments are done involving genetic engineering. In the UK there are strict laws prohibiting any experiments involving the cloning of humans. However, over the years here are some of the experimental ‘breakthroughs' made possible by genetic engineering.* At the Roslin Institute in Scotland, scientists successfully cloned an exact copy of a sheep, named ‘Dolly'. This was the first successful cloning of an animal, and most likely the first occurrence of two organisms being genetically identical.Note : Recently the sheep's health has deteriorated detrimentally* Scientists successfully manipulated the genetic sequence of a rat to grow a human ear on its back. Unusual, but for the purpose of reproducing human organs for medical purposes)* Most controversially, and maybe due to more liberal laws, an American scientist is currently conducting tests to clone himself. Genetic engineering has been impossible until recent times due to the complex and microscopic nature of DNA and its component nucleotides. Through progressive studies, more and more in this area is being made possible, with the above examples only showing some of the potential that genetic engineering shows. For us to understand chromosomes and DNA more clearly, they can be mapped for future reference.More simplistic organisms such as fruit fly (Drosophila) have been chromosome mapped due to their simplistic nature meaning they will require less genes to operate. At present, a task named the Human Genome Project is mapping the human genome, and should be completed in the next ten years. The process of genetic engineering involves splicing an area of a chromosome, a gene, that controls a certain characteristic of the body. The enzyme endonuclease is used to split a DNA sequence and split the gene from the rest of the chromosome. For example, this ge ne may be programmed to produce an antiviral protein.This gene is removed and can be placed into another organism. For example, it can be placed into a bacteria, where it is sealed into the DNA chain using ligase. When the chromosome is once again sealed, the bacteria is now effectively re-programmed to replicate this new antiviral protein. The bacteria can continue to live a healthy life, though genetic engineering and human intervention has actively manipulated what the bacteria actually is. No doubt there are advantages and disadvantages, and this whole subject area will become more prominent over time.The next page returns the more natural circumstances of genetic diversity. Genetic Engineering in Humans Science is a fascinating subject with unthinkable power. Man, the greatest creation of God and a scientific marvel, has developed the ability to genetically modify and create ‘near perfect' life. The term genetic engineering was first used in Dragon's Island, a science fic tion novel by Jack Williamson in 1951. With the discovery of ‘Deoxyribonucleic Acid' or mitochondrial DNA by James Watson and Francis Crick, this fictional plot started to turn into a reality.Watson and Crick, with their experiments, could prove that DNA was the genetic material that was transferred generation to generation, with genetic information. This genetic information determined all the characteristics of a living being. The tiny, microscopic DNA contained all the genetic information related to the person, like the color of the eyes, the hair, skin tone, height, weight, IQ, EQ, diseases, disorders, etc. and even be able to determine a smile or the shape of nose. This blueprint of life is the most important ingredient of genetic engineering.Genetic engineering is carried out using five steps, that are: Gene of interest is isolated Transfer vector is inserted into the genes The vector is transferred into the organism that is to be modified The cells of an organism are tra nsformed The last step involves selection of successfully genetically modified organisms (GMO) from those who have failed to be modified. This biotechnology was first applied to produce synthetic human insulin. This technology was gradually used to apply to a number of vaccines and drugs, that would prove to be beneficial to the human race.It was applied to plants to produce genetically modified foods, with higher resistance to infections and high nutritional values. With the advancement in technologies and major breakthroughs in genetic engineering, more and more scientists working for private and government companies are spending time experimenting with the human genes. The completion of the Human Genome Project, in 2006, has given a major opening to medical companies, to carry out experiments and genetic tests using genetic engineering.ADVANTAGES of Human Genetic EngineeringIt could help prevent life-threatening and incurable diseases like cancer, Alzheimer's disease, even HIV/AI DS. There are cases like cardiomyopathy or susceptibility to viruses, that can be overcome with the help of this technology. Better drugs could be produced that are disease or gene specific and attack the specific genetic mutation in an individual, to help over come a disease or disorder. Many people want to live a longer, healthier life or are just afraid of death. Such people with a love of life, can place their bets on it to help them live longer.It is possible to increase the average life span of an individual to 100-150 years. And not just a longer life, but a healthy, long life, free from diseases and disorders. Although this may take a bit longer to achieve, but is does not seem impossible any longer. Women have a craze to look young and maintain their beauty for all eternity. The benefits may make it possible to slow down or reverse certain cellular metabolism, that may be able fulfill this desire to remain ‘forever young' for many dreamers in the near future. You may have heard of designer clothes, designer bags, designer shoes and even a designer nose.But have you heard of designer babies? Yes, designer babies are possible to be produced with its help in humans. Parents can choose the characteristics of their babies, like blond with blue eyes, high IQ, fair skin, etc. It may even be possible to choose the talent in your favorite idol to be manufactured (pun intended! ) in your baby, for example, a singer like Elvis Presley or maybe a great dancer like Michael Jackson. No, I am not joking, this is all possible with a bit of genetic engineering, within the blueprint of life – DNA.One could even try to create super-humans by incorporating specific features of certain animals. For example, one could have super-sharp vision like the hawk or could outrun a cheetah. One could create a ‘Superman' like human who is indestructible. Do you remember ‘Dolly Sheep'? This was a genetically modified, cloned sheep that is now dead for over 6 years. This world-famous sheep was cloned using the cell from the mammary gland of another sheep. Cloning, its another aspect can also be possible. There are many ethical issues of cloning and it is considered illegal by many governments around the world.It is a crime to clone humans now, but may be in our quest to produce the perfect beings, cloning will soon become a part of life. These are a few advantages of genetic engineering in humans. But as every coin has two sides, there are many disadvantages that cannot be overlooked. Disadvantages of Human Genetic Engineering Under the pretext of producing a cure for diseases and hereditary disorders, many researchers carry out experiments on genetically modifying humans. It can prove to be a bane if: In the pursuit of producing babies without any genetic defects or hereditary disorders, we may end up producing super humans.Just as the example I mentioned in the beginning of my article, we may have a line of humans that may spell doom t o those who are not genetically modified. Smarter humans means, larger brains, that may lead to babies with larger heads that have trouble passing through the birth canal of their mothers. This may cause trouble during birth and a rise in cesarean. Long life could lead to population problems. There may be stress on the natural resources and less living space. Although, you may live free of diseases, you may have a fight for survival for securing the basic necessities.Just like in the movie Gattaca, there may be a division between genetically engineered humans and those that are normal (just imagine, begin normal may prove to be curse in the future! ). People will no longer be discriminated on the basis of race, religion or creed, but actually on their genes! Human cloning may create problems of copies of men moving about freely around the world. If your clone turns out to be the one with a criminal streak, you may end up in jail for a crime committed by your clone. It is possible, i f you can't prove your innocence. Imagine someone else taking over your life, family, work, etc!The problem faced by many developing countries today, is female infanticide. It may help stop this cruel and barbaric custom of killing the innocent girl child. You may think this is an advantage, I say otherwise. It may help such narrow-minded, biased parents to actually choose the gender of the child. Therefore, more parents opting for a male child over a girl child. Thus, directly bringing an end to girl child killing as there will be no birth of the girl child! The idea of ‘Superman' may seem tantalizing, but its consequences may be very dangerous.Imagine a person who is virtually indestructible, may carry out crimes and becomes a danger to mankind. I can go on and on regarding the benefits of genetic engineering in humans, like end of hunger, no disease, cure for all ailments, long life, ageless beauty, super intelligent humans, etc. But, one should always give a second thought to all the disadvantages listed. It is often said, man should not attempt to ‘play God'. That's correct, but if God has bestowed us the power to make some beneficial changes to his creations, then we should surely do so wisely.Genetic engineers have turned into modern-day alchemists, who are searching for the ultimate elixir of life, to produce the genetically modified, perfect human. This precious knowledge is being exploited by greedy men, who are using it just to earn more money. Nothing is bad if exploited within limits. When we harness our present, we should keep in mind all the possible effects it will have on our future. We may not be alive to view the beauty and the ugliness of the future, but our beloved children may be facing the consequences.

Ap Biology Notes Cellular Communication Essay

Cell-to-cell communication is essential in multicellular organisms. They must communicate to coordinate activities such as growth and development, and reproduction. In addition unicellular organisms communicate with each other. Signals may use light, or touch but we will focus on chemical signals. 1. External signals are converted to responses within the cell a. Evolution of cell signaling i. In yeast a cells and ÃŽ ±cells both secrete chemicals, which can only be received by the alternate type yeast. This signals the two cells to join via fusion 1. The process by which the signal on the surface of the cell is converted to a series of steps by the cell in response is called a signal transduction pathway ii. Signal transduction pathways are very similar in yeast and in complex multicellular organisms 2. This leads scientists to believe that this pathway evolved first in ancient prokaryotes b. Local and long distance signaling iii. Local signaling 3. Adjacent cells of plants and animals may communicate through cell junctions a. Signaling substances dissolved in the cytoplasm travel between cells i. Plants = plasmodesmata ii. Animals = gap junctions 4. Animal cells may use the following b. Cell-to-cell recognition iii. Direct contact between membrane-bound cell-surface molecules iv. Important in embryonic development and immune response c. Paracrine signaling v. Uses local regulators which are released and travel only a short distance to nearby cells vi. Ex. Growth factors target nearby cells to grow and divide d. Synaptic signaling vii. Electrical signal along a nerve cell triggers a chemical release across a synapse to trigger response in target cell viii. Ex. Nerve cells iv. Long- distance signaling 5. Both plants and animals use hormones e. Animals (endocrine signaling) cells release hormones which travel in the circulatory system to target cells f. Plants hormones travel in vessels or by diffusion through the air as gas g. Hormones vary in size and shape 6. Nervous system signals can also be long distance c. The three stages of cell signaling: A preview v. Reception: when the target cell detects a signaling molecule. The signaling molecule binds to a receptor protein on the target cell’s surface vi. Transduction: After binding the receptor protein is changed in some way, this converts the signal to a form that will bring about a specific cellular response 7. May occur in a single step or a series of changes vii. Response: The transduced signal triggers a specific cellular response. 8. Catalysis of an enzyme, rearrangement of the cytoskeleton, activation of a specific gene 2. Reception: A signaling molecule binds to a receptor protein, causing it to change shape d. To ensure signals are sent to the correct cell signaling molecules act as a ligand. viii. Ligand- molecule that specifically binds to another (usually larger) molecule ix. The receptor protein then usually changes shape x. May be located on the membrane or inside the cell e. Receptors in the plasma membrane xi. Water-soluble signaling molecule binds to receptor on the membrane causing it to change shape or aggregate. f. Intracellular Receptors xii. Found in cytoplasm or nucleus of target cells 9. Signaling molecule must be hydrophobic enough or small enough to pass through the plasma membrane h. Steroid hormones, thyroid hormones, nitric oxide | Examples| Pathway| Other| G-Protein Coupled Receptors| Yeast mating factors, epinephrine, hormones, neurotransmitters| 1. signaling molecule binds to the g-protein receptor 2. receptor changes shape and the cytoplasmic side binds to the inactive G protein 3. GTP then displaces to form GDP and activates the protein 4. Activated G protein diffuses along the membrane to an enzyme altering the enzyme to trigger the next step| Bacteria such as whooping cough, botulism and cholera disrupt this pathway| Receptor Tyrosine Kinases| Enzymes that catalyze the transfer of phosphate groups| 1. binding of two signaling molecules to two tyrosine chains causes the two to associate with each other forming a dimer 2. dimerization activates the tyrosine kinase region to add a phosphate from and ATP to each tyrosine in the polypeptide 3. each tail can now bind to and activate a different specific relay protein within the cell| One receptor may activate ten+ pathways. Absence can result in cancer| Ion Channel Receptors| Nervous system| 1. signaling molecule binds to the ion channel in the membrane 2. protein changes shape creating a channel through the membrane 3. specific ions can now flow through the membrane which may cause a change in the cell or trigger another pathway| Some ion gated channels are controlled by change in voltage rather than binding of a ligand| g. Intracellular Receptors xiii. Ex. Testosterone 10. Hormone passes through the plasma membrane 11. Testosterone binds to a receptor protein in the cytoplasm activating it 12. The hormone-receptor complex enters the nucleus and binds to a specific gene 13. The bound protein acts as a transcription factor, stimulating the transcription of the gene into mRNA 14. The mRNA is translated into a specific protein 3. Transduction: cascades of molecular interactions relay signals from receptor to target molecules in the cell h. Protein phosphorylation and dephosphorylation xiv. Proteins can be activated by the addition of a phosphate group (often broken off of ATP or GTP) 15. Phosphates are transferred from ATP to a protein by a general group of enzymes known as protein kinases i. Phosphorylation often causes the protein to change shape j. This happens because the added phosphate group interacts with polar or charged amino acids within the protein xv. Protein phosphatases are enzymes that remove phosphate groups from a protein 16. Mechanism for turning off signal transduction 17. These also allow for turning off and reusing pathways i. Small molecules and ions as second messengers xvi. Molecules other than proteins act as second messengers 18. Small and water soluble such as ions k. This allows them to rapidly spread throughout the cell via diffusion 19. Second messenger refers to anything after the first messenger which is the extracellular signaling molecule that binds to the membrane 20. Most common second messengers are cyclic AMP and Ca+2 xvii. Cyclic AMP as a second messenger in response to the hormone epinephrine 21. Epinephrine binds to receptor molecule protein activates adenylyl cyclase which can catalyze the synthesis of many molecules of cAMP l. Adenylyl cyclase catalyzes the conversion of ATP into cAMP ix. cAMP usually activates a serine/threonine kinase known as protein kinase A which phosphorylates many other proteins m. cAMP is converted back to AMP by phosphodiesterase xviii. Calcium ions and inositol tripohosphate 22. Increasing calcium concentration causes responses such as muscle contraction, secretion of substances, and cell division in animals, and greening in response to light in plants 23. Calcium is usually in high concentrations outside of the cell and in the ER but in low concentrations in the cytosol 24. Pathway n. Signaling molecule binds to receptor   o. Phospholipid pinches off membrane IP3 is released as second messenger p. IP3 binds to receptor on ER causing protein channel to open q. Ca+2 is released into cytosol 4. Response: Cell signaling leads to regulation of transcription or cytoplasmic activities j. Nuclear and cytoplasmic responses xix. Pathways lead to the regulation of one or more cellular activities 25. Regulate protein synthesis r. Turning specific genes on or off (calls for the synthesis of mRNA from DNA) 26. Regulate protein activity s. Cause a shape change to turn a protein on or off 27. Regulate overall shape change of cell 28. Release of mating factors 29. Cell division k. Fine-tuning of the response xx. Signal amplification 30. Enzyme cascades amplify effects by increasing the product at each step t. Enzymes stay active long enough to work on multiple products before becoming inactive xxi. The specificity of cell signaling and coordination of the response 31. Different types of cells are programmed to respond to only certain types of signals u. Some cells will respond to the same signals but in different ways v. This is because different cells have different collections of proteins xxii. Signaling efficiency: scaffolding proteins and signaling complexes 32. Scaffolding proteins increase the efficiency of the response w. A large protein with multiple protein kinases attached x. Decreases the time of the response because diffusion between proteins is not needed 33. Pathways are not linear, in fact the same protein may act in multiple pathways 34. Relay proteins serve as branch points where the signal may go in one of two directions xxiii. Termination of the signal 35. Each step in the pathway lasts only a short time, this makes the proteins ready for a new signal 36. When the signaling molecule leaves leave the receptor it reverts to its inactive form and the relay molecules follow

The Code Of Ethics A New Organization - 994 Words

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